In October 2000, the New Science Building, at Dickinson College in Carlisle, Pennsylvania was dedicated during homecoming weekend.

The structure is located across Louther Street from the Holland Union Building next to the James Center. Construction of the $13.3 million building had begun two years earlier, and classes had been held within its walls since the fall of 1999. Designed by the architectural firm of Ellensweig Associates, the new building contains enlarged classroom and laboratory space, faculty offices, and a large lecture hall in addition to the Kanev planetarium and the Britton observatory. The building houses the departments of mathematics, physics and astronomy, and computer science.

In Fall 2001, with the renaming of the Tome Scientific Building as the Stern Center for Global Education, the "New Science Building" was also rechristened as the New Tome Building.

In 1925 the Theta Chi fraternity at Dickinson College in Carlisle, Pennsylvania purchased the former Long residence at 270 West High Street, adjacent to the former home of Abram Bosler, class of 1905. Before the fraternity could move in, the house was completely remodeled at a cost of $32,000; some of the renovation included the addition of new heating and plumbing systems, a new porch, and a stucco exterior. The members dedicated their new home in 1926.

During the Second World War, the house was rented out to the College for use as a dormitory, but the members of Theta Chi returned to their home in the summer of 1946. The fraternity would occupy this house until 1964 when they moved into Quad 2 (now Buchanan Hall) in the Fraternity Quadrangle. The building was later torn down.

The longtime interest of Board of Trustees president Boyd Lee Spahr in advancing the collections and services of the Dickinson College Library in Carlisle, Pennsylvania reached its peak on November 4, 1967, when Dickinson College’s Boyd Lee Spahr Library was dedicated. It had been designed by Howell Lewis Shay and Associates, and constructed at a cost of $2,250,000.

The new library consisted 62,000 square feet of space on three levels: the main floor was used for reference and operations, while the upper and lower levels contained the stacks of books. On October 12, 1967, members of the Dickinson community participated in a book walk, which moved the entire library collection from Bosler Hall into the new Spahr Library. Two memorials were also established in the building. The Alexander A. Sharp Room for recreational reading continued first Dickinson female trustee Mary Sharp Foucht’s memorial to her father, which had been first established in the library in Bosler. The May Morris Room provided a home for the Dickinsoniana Collection, rare books, and manuscripts. May Morris, a member of the class of 1909, was the College’s longtime librarian and the second female full professor in Dickinson history.

A Second World War surplus building purchased by Dickinson College in Carlisle, Pennsylvania in 1948 became the third South College in the college history. To make the newest South College more suitable for academic purposes, the College dismantled and re-erected the building at a cost of $46,943. John K. Bixler designed the new structure, which opened in June 1948.

The new South College featured classrooms and faculty offices on the upper floors, with the lower level including a student lounge, which was later enhanced with a snack bar. When the Holland Union Building was completed, the College converted this student common area into extra classrooms and offices for the mathematics department. An indoor handball court also graced the building for years. In 1967 a portion of the building became the IBM computer center, the first such center in the College’s history, and a year later the center offered the College’s first computer science courses. The mathematics and computer science departments occupied South College until moving into a new science building in 1999. Elements of computer services also moved from the building in 2003, taking offices in the basement of the Library after the creation of the combined Library and Information Services, while the mainframe, other hardware, and its support personnel remained in South College.

Built to replace its predecessor at Dickinson College in Carlisle, Pennsylvania which was destroyed by fire in 1836, the second South College was completed on January 1, 1838. It was built to the design of Peter B. Smith, and was constructed at a cost of $5,825.

At first, the second South College contained a dormitory and classrooms for only the College Grammar School. In later years, however, the building would serve as a library, museum, and science department for the College as well. Another floor was added to the building in 1887, and the entire structure was refurnished at a cost of $5,215.

In 1927, South College was razed to provide space for the Alumni Gymnasium. A third South College was constructed behind the gymnasium in 1948.

Dickinson College in Carlisle, Pennsylvania purchased the former site of the German Reformed Church on January 7, 1835, at a cost of $2,050. This building, located opposite West College across High Street, was given the name South College, and was used as the College Grammar School until it was destroyed by fire on December 23, 1836. A new, larger South College was constructed on its site.

John Zug was born in Carlisle, Pennsylvania on March 28, 1818. Little is known of his childhood except that he began to study Latin in 1830. These studies allowed him to enter Dickinson College on September 10, 1834 as a sophomore. During his years at Dickinson College, Zug was an active member of the Union Philosophical Society, giving an address at the society's 47th Anniversary Celebration held July 4, 1836. His oratory skills appear to have been well known in both the community and the College, as he addressed several college and local groups on special occasions throughout his school career. Zug also claimed to have become "religious" on December 6, 1835. What type of event or conversion took place is neither known nor recorded, but presumably his affiliation with the Methodist Church began around that time. Zug graduated from Dickinson with the highest honors on July 20, 1837, and addressed his graduating class at Commencement. He enrolled in the law school on October 3, 1837 and was admitted to the Carlisle Bar on November 9, 1839. While at the law school, he was active in the Pennsylvania Colonial Society, serving as an agent from July 26 to November 26, 1838.

George Henry Zimmerman was born to Joshua and Elizabeth Zimmerman on September 20, 1838 in Baltimore County, Maryland. He prepared for undergraduate studies at Washington College in Maryland and then entered Dickinson College in Carlisle, Pennsylvania with the class of 1859. While at the College he became a member of Phi Kappa Sigman fraternity and was elected to the Belles Lettres Society. Following graduation in the early summer of 1859, he studied as a Methodist clergyman and was accepted as a member of the Baltimore Conference.

He filled various pastorates, including Moorefield, West Virginia between 1876 and 1879, at Easton, Maryland from 1879 to 1882, in Woodstock, Virginia 1886-1888, West River, Maryland 1888-1892, and Hyattsville, Maryland 1892-94. He was a presiding elder over the Roanoke District between 1882 and 1886 and over the Moorefield District between 1894 and 1898. In 1898 he took up the editorship of the Christian Advocate, shortly before his death.

In October 1866, he had married Henrietta Ann Rowe of Charles County, Maryland and the couple had three sons. George Henry Zimmerman died on November 3, 1898. He was sixty years old.

John C. Young was born in Greencastle, Pennsylvania on August 12, 1803 to John and Mary Clarke Young. His father and his uncle were Presbyterian ministers, and he quickly determined to follow that course. To that end, he was educated at home and then at a classical school in New York City, before entering Columbia College there. After three years at Columbia, he withdrew and entered Dickinson College in Carlisle, Pennsylvania, where he graduated with the class of 1823.

John Young was born on September 4, 1763 in York County, Pennsylvania. Little is known of his early life prior to his enrollment in Dickinson College in Carlisle, Pennsylvania. As a member of the Class of 1788, Young studied under President Charles Nisbet and took fastidious notes. Because of Young's attentiveness, transcripts of Nisbet's lectures on theology, philosophy, and metaphysics survive and are housed in the College's Archives and Special Collections.

After receiving his bachelor's degree in 1788, Young remained at Dickinson to continue his studies in theology with Nisbet, as did several of his classmates. Although he did not earn any advanced degree, Young was licensed to preach by the Philadelphia Presbytery in 1791, and the following year he became the pastor at churches in Timber Ridge and Old Providence, Virginia. His pastorship in Virginia lasted for seven years; he relocated to Greencastle, Pennsylvania in 1799. There he preached until his death in 1803. In 1802, Young became a trustee of Dickinson College.

Young married Mary Fullerton and the couple had at least one son, John Clarke Young, who graduated from Dickinson in 1823 and went on to become president of Centre College in Kentucky. John Young died on July 24, 1803, less than a month before his son John was born.